Charcoal Stripped Fetal Bovine Serum | 500mL

SKU: 11-09CS-500
In stock
In stock for cold-chain shipment
Regular price $660.00 USD
Heat Inactivation

Need to qualify this lot before scaling? Request a 50 mL evaluation sample or send the intended volume.

Product identifiers

  • Type Specialty Fetal Bovine Serum
  • Documentation: COA, COO, and lot file route through the lot-document request below.
  • Sample path: 50 mL evaluation request available before scale-up.

US Origin fetal bovine serum charcoal/dextran stripped to remove steroid hormones, growth factors, and lipophilic compounds. The charcoal stripping process significantly reduces estradiol, progesterone, testosterone, cortisol, and thyroid hormones — creating a hormone-depleted serum essential for steroid receptor research and hormone-sensitive cell culture.

Key Features
  • Charcoal/dextran treated to remove steroid hormones and lipophilic compounds
  • Reduced estradiol, progesterone, testosterone, cortisol, T3, T4
  • US Origin, triple 0.1µm sterile filtered
  • 9CFR virus panel tested
  • Lot-specific Certificate of Analysis with hormone depletion data
  • Available not heat inactivated or heat inactivated
Specifications
Specification Detail
Origin United States
Treatment Charcoal/dextran stripped
Volume 500 mL
Hormones Reduced Estradiol, progesterone, testosterone, cortisol, T3, T4
Filtration Triple 0.1µm sterile filtered
Virus Testing 9CFR panel
Storage -20°C; thaw at 2–8°C
Endotoxin < 10 EU/mL
Hemoglobin < 25 mg/dL
pH (neat) 6.8–7.5
Osmolality 280–340 mOsm/kg
Applications

Steroid receptor research, hormone-sensitive cell lines (MCF-7, T47D, LNCaP), nuclear receptor assays, endocrine disruption studies, and any protocol requiring hormone-free serum supplementation.

Need a quote, COA, or bulk pricing? Contact our team or request a quote directly from this page.

Lot-specific documentation routes through the FBS documentation page.

Use the lot number from the bottle, quote, or packing slip to request COA, COO, traceability, and handling files.

Open FBS documentation downloads

Volume Discounts

Volume discounts on 500 mL: 6+ units 10% off | 12+ units 18% off | 24+ units 26% off | Larger orders? Contact us for additional savings.

Variant Quantity Price Total
Not Heat Inactivated 11-09CS-500
Regular price $660.00 USD
$0.00
Regular price $660.00 USD
$0.00
Heat Inactivated (+$10) 11-09CSHI-500
Regular price $670.00 USD
$0.00
Regular price $670.00 USD
$0.00
0 Total items
$0.00 USD

Product subtotal

Specifications

What this lot delivers

Bench-grade specifications. Lot values are reported on the COA shipped with every order.

OriginUSDA-Approved origin, WOAH-classified BSE negligible-risk, traceable, charcoal stripped after source qualification
TreatmentDextran-coated activated charcoal stripped to reduce lipophilic hormones and lipid-soluble compounds
Stripping efficiencyLot-specific residual hormone values reported on COA, typically less than 5% versus standard FBS
GradeCharcoal-stripped research grade for hormone-response, endocrine, and low-background receptor studies
FiltrationTriple 0.1 µm sterile filtered
EndotoxinLot value on COA
HemoglobinLot value on COA
Virus testingStandard virus panel reported on COA
StorageLong term: minus 20 deg C. Short term: 2 to 8 deg C, up to 2 weeks unopened
Shipping conditionFrozen on dry ice, cold-chain
Quality systemISO 9001 and ISO 13485 dual-certified
Industry membershipInternational Serum Industry Association (ISIA)
Viral safety9 CFR Part 113.53 virus panel, lot result on COA
Growth promotionRGP assay on fastidious human diploid fibroblasts, lot value on COA
Sterility detailMycoplasma direct-culture plus Hoechst stain, sterile filtration documented by lot
Supply chainWOAH-classified BSE negligible or controlled-risk regions, documented chain of custody
Shipping and returns
Dry iceFrozen on arrival
Lead timeQuoted at order
Non-returnableDamage replaced
Damage pathPhoto, email, replacement

Vendor file

Standing documents and buyer guides

Core PDFs and decision pages for vendor setup, protocol review, and internal purchasing files.

Size and treatment matrix

Pick the active variant, route the rest.

Use the live selector in the buy box for stocked options. Special handling, case volume, and evaluation volume route to the correct page.

OptionSKUStockPricePath
Not Heat Inactivated 11-09CS-500 In stock $660.00 Select
Heat Inactivated (+$10) 11-09CSHI-500 In stock $670.00 Select

Decide once

How to choose this grade

Five buyer paths and the honest verdict for each. Pick this grade only if your job-to-be-done is in the list.

01

Hormone-response or endocrine work

Steroid, thyroid, estrogen, androgen, growth-factor background

Yes, this grade. Charcoal-stripped FBS reduces endocrine-active background while preserving cell-culture viability. Use it when serum hormones would confound dose response, receptor activation, or pathway readouts.

02

Receptor-binding or steroid signaling

ER, AR, GR, PR, thyroid receptor, ChIP-seq

Yes, this grade. Use for low-background receptor-binding studies, steroid receptor ChIP-seq, and ER-positive or AR-positive cancer models where residual hormone signal must be controlled lot by lot.

03

Routine mammalian culture

HeLa, CHO, HEK293, MDCK

Use only if documentation requires it. Standard FBS is usually the better value for routine growth. Charcoal-stripped FBS carries a cost premium and may alter growth behavior without improving non-endocrine workflows.

04

Stem or primary cells

iPSC, MSC, T cells, primary hepatocytes

Request a sample first. Hormone and lipid-soluble compound depletion can change attachment, proliferation, or differentiation behavior. Pilot the exact lot before scale-up, especially for sensitive primary or stem-cell systems.

05

FDA-regulated workflow

IND, BLA, GMP-adjacent, sponsor mandate

Confirm the protocol requirement. Choose charcoal-stripped only when the method requires hormone-depleted serum. If the gating issue is geographic origin or regulatory traceability, route the requirement through documentation review first.

Field reports

How this lot performs in other labs

Direct lab feedback from Judge.me. We show field reports only when there are at least three; if not, this section stays hidden.

5 ★
4 ★
3 ★
2 ★
1 ★

Lot documentation

Request the COA, COO, or origin file

Send us your bottle, quote, or packing-slip lot number and we route the COA, COO, traceability statement, and handling file. Handled by a real person on the procurement team during business hours.

Lot document request

Handled by procurement during business hours.

Cold chain

Frozen fulfillment for lab receiving

Dispatch rules, packaging, and freight options for receiving-dock planning and purchase-order notes.

Processing schedule

Orders before 2 PM PT Monday through Wednesday ship the same business day. Thursday orders ship Friday morning for Saturday delivery.

Parcel cold chain

UPS Next-Day Air ships with validated dry ice packaging at no additional charge. Temperature monitoring is included on every shipment.

Bulk freight

Orders of 300+ bottles qualify for frozen LTL freight, temperature-controlled palletized shipping, coordinated delivery scheduling, and bulk-pricing review through procurement.

Side-by-side

What we publish that they do not

Public-data comparison against Sigma-Aldrich F0926 and Gibco A5670201, both standard FBS shown as procurement and documentation reference points. Sigma-Aldrich C8056 and Gibco A3382101 are the grade-matched charcoal-stripped equivalents if you need a head-to-head spec comparison.

Spec Innovative Bioscience Sigma-Aldrich F0926 Gibco A5670201
Origin and treatmentUSDA-Approved origin, traceable, charcoal stripped after source qualificationStandard FBS, not charcoal strippedStandard FBS, not charcoal stripped
FiltrationTriple 0.1 µm sterile filtered0.1 µm sterile filteredTriple 0.1 µm sterile filtered
EndotoxinLot value on COAReported on COAReported on COA
HemoglobinLot value on COAReported on COAReported on COA
PricingVisible on this pageSign-in or quote required for many SKUsVisible
COA accessRequest per lot, handled by procurementLot lookupLot lookup
Sample policyFree 50 mL evaluation, dry-ice shippedBy rep, often chargedBy rep
Cold-chain dispatchCold-chain validated, lead time at quoteLead time per warehouseLead time per warehouse

Comparison drawn from publicly available product pages, updated as competitor specs change. Verify with their datasheet for any time-sensitive procurement decision.