We offer 11 FBS products across 4 countries of collection and 5 specialty treatments. Every product undergoes triple 0.1µm sterile filtration to a sterility assurance level of 10⁻³, 9CFR virus panel testing, and ships with a Certificate of Analysis and Certificate of Origin. Use the tables below to compare by origin, treatment, or price.
FBS Product Comparison Guide
Compare origin, specifications, and pricing across our complete Fetal Bovine Serum catalog to find the right product for your research.
Our FBS Catalog
Every lot ships with COA, frozen on dry ice
FBS Specifications by Origin
All products triple 0.1µm sterile filtered. Heat inactivation available for +$10 on all standard products.
| Product | 500mL | Endotoxin | Hemoglobin | pH | Osmolality |
|---|---|---|---|---|---|
| US Origin FBS | $595 | ≤5 EU/mL | ≤25 mg/dL | 7.0–8.0 | 280–360 |
| US Origin FBS Advance | $625 | ≤5 EU/mL | ≤25 mg/dL | 7.0–8.0 | 280–360 |
| USDA Approved FBS | $425 | ≤5 EU/mL | ≤25 mg/dL | 7.0–8.0 | 280–360 |
| USDA Approved FBS Advance | $495 | ≤5 EU/mL | ≤25 mg/dL | 7.0–8.0 | 280–360 |
| Australian Origin FBS | $695 | ≤5 EU/mL | ≤25 mg/dL | 7.0–8.0 | 280–360 |
| NZ Origin FBS Advance | $725 | ≤5 EU/mL | ≤25 mg/dL | 7.0–8.0 | 280–360 |
| Charcoal Stripped | $660 | Specialty — contact for lot-specific specs | |||
| Dialyzed | $660 | Specialty — contact for lot-specific specs | |||
| Gamma Irradiated | $750 | Specialty — contact for lot-specific specs | |||
| Exosome Depleted | $1,750 (250mL) | Specialty — contact for lot-specific specs | |||
Prices current as of March 2026. Specifications represent published acceptance criteria per COA. Actual lot results typically exceed these standards (e.g., endotoxin results often <0.1 EU/mL). Lot-specific COA available for every product.
FBS by Origin
US Origin FBS
US Origin FBS comes from cattle born and raised exclusively within the United States. This origin provides the highest level of domestic traceability and is the standard choice for NIH-funded research requiring US-sourced materials.
- Full USDA domestic traceability from collection to delivery
- Tested for bovine viruses (BVD, IBR, PI3, BRSV), mycoplasma, sterility, endotoxin, and hemoglobin
- Standard ($595/500mL) and Advance ($625/500mL) grades available
USDA-Approved Origin FBS
USDA-Approved Origin FBS is collected in countries with USDA-approved BSE negligible-risk status, imported under USDA permit with full regulatory documentation. Both origins are classified as BSE negligible risk by WOAH.
- USDA/APHIS approved import with full documentation
- ISIA traceable for supply chain transparency
- Best value for labs that do not require domestic-only sourcing — $425/500mL
Australian Origin FBS
Australian Origin FBS comes from Australia’s BSE-free cattle population. This origin is preferred by researchers conducting work for international regulatory submissions or those requiring geographic isolation from BSE-affected regions.
- BSE-free geographic origin recognized by OIE
- Gamma-irradiated option available for additional biosafety
- Premium grade at $695/500mL
New Zealand Origin FBS
New Zealand maintains some of the strictest animal import controls in the world, making NZ Origin FBS a premium choice for researchers requiring exceptional biosafety credentials.
- Geographic isolation from BSE-affected regions
- Stringent government oversight of animal products
- Advance grade with extended hormonal profiling — $725/500mL
Specialty FBS Products
Charcoal-Stripped FBS — $660/500mL
Charcoal stripping removes hormones, growth factors, and lipophilic molecules from serum while preserving essential proteins. Essential for:
- Estrogen and androgen receptor studies
- Steroid-sensitive cell proliferation assays
- Drug screening where endogenous hormones could confound results
Dialyzed FBS — $660/500mL
Dialysis removes small molecules (typically below 10 kDa molecular weight cutoff) while retaining larger serum proteins. Use dialyzed FBS when your protocol requires:
- Defined amino acid or glucose concentrations
- Metabolic labeling experiments
- Studies where small-molecule contaminants could interfere
Gamma-Irradiated FBS — $750/500mL
Gamma irradiation provides an additional layer of biosafety by inactivating potential adventitious agents. Recommended for:
- Work in BSL-2+ containment facilities
- Applications requiring maximum biosafety assurance
Exosome-Depleted FBS — $1,750/250mL
Exosome-depleted FBS has been ultracentrifuged to remove extracellular vesicles, making it essential for researchers studying exosome biology, cell-to-cell communication, and extracellular vesicle characterization.
ORIGIN & QUALITY
How to Choose the Right FBS
Selecting the right FBS depends on several factors:
- Regulatory requirements: NIH-funded or FDA-regulated work typically requires US Origin FBS. International collaborations may need Australian or NZ origin.
- Application specificity: Hormone studies need charcoal-stripped. Metabolic research benefits from dialyzed. Exosome research requires exosome-depleted.
- Budget: USDA Approved FBS at $425/500mL offers excellent quality at our most competitive price point.
- Lot consistency: Take advantage of our lot matching service to reserve lots that work well with your cell lines.
Decision framework: Consider regulatory requirements (NIH-funded work typically requires US Origin), application specificity (hormone studies need charcoal-stripped, metabolic research benefits from dialyzed), and lot consistency (use our lot matching service to reserve lots that work with your cell lines).
Trusted by Research Labs
Their pricing was competitive, their replies always fast and courteous, and their FBS fared better against HyClone and Corning.
The products are great especially the Heat inactivated FBS, tubes and tips. Super professional and always happy to help.
Switched from Gibco to save on budget and can't tell the difference in our CHO-K1 growth curves.
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Request a Sample
We offer 50 mL evaluation sizes so you can test our FBS in your own assays before committing to a full purchase. Every evaluation sample ships from the same lot as the full-size bottles, with a complete Certificate of Analysis.
We will ship your samples with full Certificates of Analysis and lot-specific documentation.
Ready to Test?
50mL evaluation sizes from $42.50 — test in your cell lines before you commit.
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Heat Inactivated vs Standard
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